"； Do you want to do this; Fatal temptation... Challenge Game : The floral artist Ae-ran (Vicky) and forensic investigator Min ho (Choi Ryeong) from the prosecutor's office both have a family that everyone wants. However, Min ho cannot control her sleeping time, so Ae-ran begins a challenge game in which she seduces unfamiliar men and has sex with them. One day, Ae-ran and Min ho met Alex (played by Choi Hyun ho) at a tango caf é. Alex is interested in and approaches Ae ran, who is more handsome than her husband Alex. Min ho later witnessed their actions and was very angry when he found out that the man Ae ran was luring was Alex. Min ho felt nervous because he realized that Alex was not just a competition partner, so he came to him for a reason. Min ho tried to get rid of Alex, but Alex even grabbed Ae ran and Min ho, feeling the release. The game they started is turning into a disaster...
但因为药剂有副作用，也因此造成20亿人的发病，间而诞生「嗜血种」这样的新生命体。之后，“嗜血种”与人类之间的战争爆发, 虽然最后以人类方的胜利收场，但是残留下来的嗜血种却还是存在于这个世界上….。最终，人类凭着人造血液及被称为“D-GPS”的嗜血种管理系统，来保障嗜血种的生存权利。 这个故事，是在人类与嗜血种共存为日常生活的舞台上进行的。
安娜（达科塔·约翰逊饰）在出版业找到了一份很有前途的新工作，并准备开始她的新生活。格雷（杰米·多南饰）仍在对安娜进行热情的攻击。尽管安娜已经决定摆脱过去的物种，但她仍然无法抗拒格雷的魅力。最后，在格雷承诺他会做出改变后，安娜再次接受了他。
